Eukaryotic chemotaxis
نویسندگان
چکیده
منابع مشابه
Cellular memory in eukaryotic chemotaxis.
Natural chemical gradients to which cells respond chemotactically are often dynamic, with both spatial and temporal components. A primary example is the social amoeba Dictyostelium, which migrates to the source of traveling waves of chemoattractant as part of a self-organized aggregation process. Despite its physiological importance, little is known about how cells migrate directionally in resp...
متن کاملMolecular insights into eukaryotic chemotaxis.
Many cells display directed migration toward specific compounds. The best-studied eukaryotic models of chemotaxis are polymorphonuclear leukocytes, which respond to formylated peptides and Dictyostelium amoebas, which respond to extracellular cAMP. In both cell types, chemoattractants bind to surface receptors that contain seven transmembrane domains and interact with G proteins. Some cells, su...
متن کاملThe physics of eukaryotic chemotaxis.
www.physicstoday.org A small scratch on the skin can be quite painful. Fortunately, the pain is transitory and dissipates quickly once the wound heals. The healing process is facilitated by neutrophils, a type of white blood cell that removes bacteria and other foreign materials from a wound. Neutrophils normally reside in your circulatory system but, when needed, are able to leave the bloodstr...
متن کاملAssays for eukaryotic cell chemotaxis.
Chemotaxis is essential for many biological processes. Much of our understanding of the mechanisms underlying chemotaxis is based on a variety of in vitro assays. We review these assays, dividing them into groups depending on the process used to generate the gradient. We describe how each method works, its strengths and limitations, and provide some information about the kinds of cells that hav...
متن کاملEukaryotic chemotaxis at a glance.
Introduction Chemotaxis is a fundamental process in which cells migrate directionally when they are exposed to external chemical gradients. It is exhibited by a wide variety of cell types and involves distinct strategies that depend on the environmental conditions. For example, the migration of fibroblasts or keratinocytes within tissues is relatively slow as it relies on strong adhesion forces...
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ژورنال
عنوان ژورنال: Wiley Interdisciplinary Reviews: Systems Biology and Medicine
سال: 2009
ISSN: 1939-5094,1939-005X
DOI: 10.1002/wsbm.28